FROM PBLS TO PERIODIC BREATHING: THE MOUNTAINS HAVE A SYLLABUS OF THEIR OWN
If you had told first-year me, fresh out of board exams, running on the hospital canteen’s ‘doctor set’ and Chiya, that one day I would be treating patients at 4,410 meters, making independent emergency decisions with limited resources, I would have laughed, panicked, and probably asked if there was WiFi. And yet, here we are.
In April 2019, I went on a solo trek to Gosaikunda, thinking it would be a short break in between the PBLs. I returned with sore legs and a sunburn I did not ask for. I didn’t know then that the mountains were quietly preparing a syllabus of their own, one that would shape how I understood both medicine and myself. The thin air, biting cold, and overwhelming silence humbled me in a way no viva ever had. Somewhere between struggling for breath and staring at snow-covered ridges, I developed a deep respect and passion for life at high altitude.
That trek opened a door I kept walking through-Annapurna Circuit, Annapurna Base Camp, Paanchpokhari, Tsho Rolpa, Tilicho, and eventually Manaslu Circuit. Each journey taught me something textbooks never explicitly say: endurance is learned slowly, resilience is built step by step, and rushing- whether up a mountain or through life- comes with consequences. I even experienced symptoms of acute mountain sickness (AMS) myself, which turned a theoretical concept into a very real headache, nausea, and a lesson in humility. It made me a more attentive trekker and later, a more empathetic doctor.
I first heard about the Manaslu Circuit in February 2020, from a group of porter brothers at Thorong High Camp enroute Annapurna Circuit trek. We were all gathered around a heater, sipping warm water like it was luxury tea, sharing life stories, and mentally preparing for Thorong Pass(5416m) the next morning. This was right after our first-year board exams, when simply surviving felt like success. They said Manaslu was the toughest trek they had ever done-steep, relentless, no mercy. At that time, it felt impossible. Medical school schedules were tight, leaves were rarer than full sleep cycles, and while we managed shorter treks, Manaslu stayed on the “maybe someday” list. Someday finally cameimmediately after our final board exams.
Manaslu became my eighth and final trek during medical school, and fittingly, the most transformative. We moved every day- no two meals at the same place. Every trek is part torture, part therapy. Days start before dawn and stretch into 12 hours of walking. My legs scream, my lungs protest. Ironically, we hustle more than we ever did in college, yet feel freer than ever. Crossing Larke La Pass is the closest I’ve come to questioning all my life choices and loving every excruciating, breathtaking step of it. As the body grows tired, the mind grows clearer. The heart is the happiest, and the mind at an unbelievable peace. Who knew exhaustion could feel so therapeutic?
Fast forward to today: I now work as a licensed medical practitioner at The Mountain Medical Institute, Dingboche(4410m), at an altitude where even walking to the toilet counts as cardio. I see how seamlessly those journeys prepared me for this role. Who knew I would be writing this article with this magnificent view of Mt. Aama Dablam right in front of my eyes, surrounded by Mt. Thamserku, Kang Tenga, Kang Thari, Lobuche, Cholatse, Island peak on all sides.
At Dingboche, I manage everything from altitude illnesses and trauma to chronic outpatient conditions. I provide inpatient care, stay on 24/7 emergency call, perform minor procedures, make independent clinical decisions in a resource-limited setting, and very importantly, I am learning to rely on my training. In just over a month, I saw 332 patients, 156 foreigners, 176 locals, including 17 critically ill for whom immediate helicopter evacuation was done.
There are cases of AMS, HAPE, HACE, respiratory infections, gastrointestinal illnesses most commonly traveller’s diarrhea, polycythemia, hypertension, Khumbu cough, tendon rupture, dental abscess, intestinal obstruction, cellulitis, scabies, alcohol withdrawal, STDs, UTI, epistaxis, hyperventilation syndrome, IDA, Paronychia, Cheyne Stokes Breathing, electrolyte imbalances, arrhythmias(PAC/PVC), periodic breathing of altitude, musculoskeletal injuries, frostbite, Scalp laceration caused by impact from a rock sliding down a hill, bladder outlet obstruction and emergencies that tests every bit of my training and intuition.
Some cases stay with me deeply: a porter brought in semi-conscious with no informant, later developing seizures and found out after tracking down his family members with great difficulty and thorough history taking that he had stopped antiepileptic medication; a three-year-old local child with dangerously low oxygen saturation and febrile seizure; a young trekker whose persistent headache was like a puzzle unsolved; and frostbite cases- trekkers who lost their way and spent a night outdoors above 4,900 meters.
Working at altitude taught me what medical school never fully can: clinical judgment sharpens when investigations are limited, prioritization becomes instinctive, and endurance isn’t optional. Long nights, early morning evacuations, and full OPDs the next morning test not just knowledge, but endurance beyond textbooks. It is exhausting, humbling, and profoundly rewarding.
Years ago, I had attended altitude sickness classes at PAHS by Dr. Buddha Basnyat. Today, those lessons feel less like lectures and more like preparation for where I’m meant to be.
To my juniors especially: medical school is important, but it is not life in its entirety. Study sincerely but also rest, travel, laugh, make memories, and take care of yourself. Burnout is real. Refreshment is not laziness or luxury; it is survival. You cannot pour from an empty cup, especially when you’re expected to save lives. Life is short. Experience it in all its shades. Make memories with friends while you still can. Walk when you can, pause when you must, and don’t forget to live your own life while learning how to save others.
Working in the mountains is hard – unpredictable weather, limited resources, long hours, but it is also deeply fulfilling. The challenges are real, but so is the reward. And sometimes, the hardest paths are the ones that quietly lead you home.
With love, gratitude, and very tired legs,
Dr. Sarmita Shrestha, 26
Patan Academy of Health Sciences
MMSN Blogs 2026 | January
ALTITUDE, DIURESIS, AND PERSONAL OBSERVATIONS
Few months ago, Me along with my friends went on a trek to Paachpokhari. The altitude of Paachpokhari is 4100 m above sea level. As a medical student, the first thing in mind after hearing the word Trek is Acetazolamide and Acute Mountain Sickness abbreviated as AMS. Two utmost things for AMS are headache and recent gain in altitude(above 2500 m). Similarly, few weeks ago I also went on a trek to Gosainkunda. Its altitude is 4380 m.
Now, let’ s talk about the differences and similarities between these two treks. One of the differences is that I was able to complete the trek to Paachpokhari but not to Gosainkunda(haha). The similarity is, I didn ‘t take Acetazolamide in either of the treks as far as I remember.The most important part of these 2 treks that I want to share is Diuresis.
During our Journal club session, one of my seniors shared that there is a difference between how our body responds to gain in altitude based on whether we are highlanders(TH) or low-landers(LL). I was born in Kalikot which is around 2033 m whereas I spent most of my childhood in Kailali whose altitude is around 186 m and then in Kathmandu which is around 1400 m.
According to this paper, Diuresis is the renal compensatory mechanism for Respiratory alkalosis which is more prominent in high landers. I wanted to share an interesting observation that I noticed in these treks. I was urinating more frequently than I normally do (about twice per hour in Gosainkunda Trek). I don ‘t have a good memory of Paachpokhari but I remember I was urinating frequently during that trek as well. This has led me to strengthen the point that I might have the gene of Tibetan high lander.
Regards
Mr. Ramesh Rokaya, 23
Maharajgunj Medical Campus
